| ncRNA name | SHH shRNA |
| ncRNA Category | shRNA |
| Disease name | retinoblastoma (RB) |
| Species | Homo sapiens |
| Tissues/Cell_line | RB cell line WERI-RB1 |
| Methods | shRNA knockdown, qRT-PCR, Western blot, MTT assay, flow cytometry, colony formation assay |
| Expression pattern | associated |
| Functional description | The silencing of SHH induced G1 cell-cycle arrest and apoptosis in WERI-Rb-1 cells and led to a decrease in cell viability. |
| PubMed ID | 28943916 |
| Year | 2017 |
| Title | Blockade of sonic hedgehog signaling decreases viability and induces apoptosis in retinoblastoma cells: The key role of the PI3K/Akt pathway. |
| Drug-related ncRNA | NA |
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